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We’re fully re-open!

And taking every precaution to keep you safe

  • Masks are required
  • Patients will be roomed immediately upon entry *when possible
  • Temperatures will be taken
  • No companions will be allowed at your visit (we ask that they wait in the car)
  • COVID Screening for patients and staff will be conducted daily


At All Star Pain Management and Regenerative Medicine, we want to make relieving your pain our priority. With board-certified pain relief physicians, a reputation for exceptional patient care and a variety of treatment options, we consistently offer life-changing procedures for our patients in the Annapolis, Greater Baltimore and Washington D.C. areas.

Our founder, Dr. Zvezdomir Zamfirov (Dr. Zed), established All Star Pain Management and Regenerative Medicine on pillars of integrity, respect, compassion and perfectionism. Dr. Zed’s goal has always been to decrease his patients’ pain and return them to their previous levels of activity. We understand how difficult and debilitating living with chronic pain can be, which is why we have made it our mission to help you get back to living your life your way. It’s time you take back control of your life, and All Star Pain Management and Regenerative Medicine is here to help you do just that.

About Us


Karen brings 17 years of experience in pain management with a focus on physical and nutritional medicine, as well as previous experience in orthopedic surgery. She specializes in developing individualized care for each patient. She has a strong educational background from the George Washington University School of Medicine where she simultaneously earned her Physician Assistant degree and her Masters of Science in Health Science in 2003. She earned her Bachelor’s Degree from the University of Vermont in 1998. She is certified by the National Commission on Certification of Physician Assistants and is a member of the American Academy of Physician Assistants. She earned a Top Performer award for overall patient satisfaction for multiple years. She practices what she preaches by maintaining an exceptionally healthy and active lifestyle! She is an avid runner and paddleboarder and enjoys boating and spending time on the water.

Discover Our Wellness Center

Get Back to Doing What You Love

Injuries and chronic pain can prevent you from pursuing a healthy and active lifestyle, which is why the experts at All Star Pain Management and Regenerative Medicine are here to provide support, compassion and life-changing treatment. The interventional and regenerative therapies we offer aim to target pain at its source for effective and lasting treatment. Our patients commonly come to us with the following concerns:

  • Lower back pain
  • Neck pain
  • Sports injuries
  • Tendonitis
  • Arthritis
  • Chronic joint pain

If you suffer from any of the above conditions, schedule a consultation with Dr. Zed today to learn how we can relieve your pain and meet your unique needs.


Do you want to know if you are a candidate for stem cell therapy? Have you heard of this treatment option but don’t know if it is an option for you? If so, please take our survey to see if your symptoms or conditions are something that can be treated with stem cell or other regenerative medicine treatments. Most patients who are a candidate did NOT know that these therapies were an option for their conditions. We look to provide natural healing and avoidance of surgery whenever possible!

This short survey will identify some of the most common musculoskeletal conditions treated by our office with stem cell therapy. We are also available to answer any and all of your questions following the survey by contacting our office.

Online Survery

The Latest in Minimally Invasive & Cutting-Edge Therapies

Our minimally invasive, evidence-based treatment options provide you with the pain relief you need without an uncomfortable or lengthy recovery from open surgery. We focus not only on treating pain at its source but also repairing and regenerating the injury or orthopedic condition that causes you pain in the first place. Helping you avoid surgery and other more invasive treatment options means you get to enjoy a pain-free lifestyle that much sooner.

Some of the many cutting-edge treatments we offer include:

We understand that no two patients are the same, which is why we employ individualized and personalized treatment programs for all of our patients. Dr. Zed will take the time to truly understand your unique concerns and trace your pain back to its source at the start of your treatment, personally guiding you toward a pain-free lifestyle step-by-step.

Meet Our Pain Relief Experts, Your Team for Life

As a former professional Bulgarian soccer player, Dr. Zed established a passion for helping athletes overcome their sports-related injuries early on. Dr. Zed received his medical degree from the Plovdiv Medical University in 1987 and proceeded to practice as an orthopedic surgeon in Bulgaria for many years, treating a large number of high-level professional athletes. Upon moving to the United States, he completed his Physical Medicine and Rehabilitation Residency at Georgetown University and has been treating patients in the Baltimore/Washington Metro since 2007. In 2017, Dr. Zed opened All Star Pain Management and Regenerative Medicine.

Dr. Zed

Dr. Zed is board-certified by the American Board of Physical Medicine and Rehabilitation. He is personally involved with all of our patients’ care from start to finish, ensuring you receive the highest-quality treatment from the moment you enter our offices until the moment you leave.

Daniel Sheehan, MD

Janet Ascione, NP-C

Janet Ascione, NP-C, brings several years of nursing experience and genuine compassion, kindness and professionalism to her patients at All Star Pain Management and Regenerative Medicine. With board-certification from the American Academy of Nurse Practitioners and a master’s degree in nursing, Janet provides all of our patients with her certified expertise and a natural aptitude for extraordinary patient care.

Patrick Comegys, PA

Patrick Comegys, PA, has recently joined our practice, adding his extensive orthopedic experience and skill to our team. Patrick graduated from Salisbury University and received his PA degree from Towson University. He continued to improve his education and garner valuable experience working in emergency medicine at the University of Baltimore Washington Medical Center. Patrick eventually transitioned to orthopedic medicine, which he has been specializing in for more than eight years.

Karen Scott PA-C, MSHS

Karen brings 17 years of experience in pain management with a focus on physical and nutritional medicine, as well as previous experience in orthopedic surgery. She specializes in developing individualized care for each patient.

Our entire team is made up of qualified pain relief experts with extensive training in orthopedic and regenerative procedures. Schedule a consultation at All Star Pain Management and Regenerative Medicine to learn for yourself why we are the leading experts in pain relief and regenerative medicine.

Dr. Zed Featured On Midday Maryland