25 Jan How do Stem Cells – the Body Healers Work?
Stem cells have the ability to move to injured tissues. This occurs when the body suffers an injury or a disease which signals their release and migration to the distressed cells/tissue. Once stem cells reach the site of injury, they ‘dock’ on adjacent cells to begin their job.
Stem cells serve as replacement cells and change into the required cell type at the site of damage, such as a muscle or ligament cell. This is a perfect solution for traumatic injuries and orthopedic conditions.
The absence of specific HLAs expression allows stem cells to avoid fighting or elimination by the immune system. When they dock on a cell, they release growth factors, called cytokines and chemokines. These growth factors help in systemic control of many aspects –
- Controlling the immune system and regulating inflammation – This is a key mediator of diseases of aging and autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.
- Aid new blood vessel formation to add vasculature – This allow proper blood flow and the correct nutrients to reach the site of injury and damage, for example, in stroke, peripheral artery disease and heart disease.
- Provide trophic support for surrounding tissues and help host endogenous repair – This is again great for orthopedic issues, since it releases signals to activate your own stem cells to repair the tissue.
All these factor allows stem cells great healing potential in several diseases and injuries.